Articaine with adrenaline forte


In case of Adrenaline (epinephrin) availability in Articaine medicine with adrenaline forte is prolonged effect of medicine, the risk of developing of bleedings in the field of surgical intervention decreases. On the other hand, adrenaline interferes with excessive absorption of an articaine and development of its side effects. Articaine with adrenaline forte surpasses lidocaine and mepivacaine in the anesthetizing action several times more when carrying out infiltration and conduction anesthesia.

Dosage form:

Injections liquid (40 mg + 0,01 mg)/ml

Registration number:


International unlicensed name:

Articaine + epinephrin

Pharmacotherapeutic group:

Local anesthetic + alpha- and beta-adrenoceptor agonist

ATX code:


Application indication:

Infiltration anesthesia of interventions on upper jaws and in a forward site (including bicuspid teeth) lower jaws, conduction anesthesia.


Hypersensibility to an articaine, an epinefrin, sulfites (intolerance of sulfonate groups – especially at bronchial asthma) or to any other from auxiliary components of a preparation.
The contraindications relating to an artiсaine:

  • malfunction of sinoatrial node or heavy violations of conductivity (such as, the expressed brachycardia, second and third antegrade block stages);
  • acute decompensated heart failure;
  • arterial hypotension;
  • anemia (including Biermer disease);
  • methemoglobinemia;
  • hypoxia;
  • children under 4-year age (there is no experience of clinical application).

Epinefrin existence contraindications:

  • Bouveret’s disease, tachyarrhythmia, narrowangle glaucoma;
  • simultaneous reception not selective beta adrenoceptor blocking agent (risk of hypertensic crisis and the brachycardia);
  • hyperthyroidism;
  • pheochromocytoma;
  • hyperpiesis.
Release form:

5 ampoules in planimetric plastic package (pallet) or planimetric cell package. 1 or 2 planimetric plastic packages (pallet) or planimetric cell package and application instruction in a box made of cardboard.

Hospitals packaging:

20, 50 planimetric plastic packages (pallets) or planimetric cell packages with ampoules and apllication instructions in the box made of cardboard.